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The GIP pathway appears to provide additional metabolic benefits without adding the gastrointestinal side effects that come with higher GLP-1 doses

doi: 10.1152/ajpgi.00242.2016 13 CamilleriM.ShinA.BusciglioI.CarlsonP.AcostaA.BharuchaA

Chakhtoura M., Haber R., Ghezzawi M., Rhayem C., Tcheroyan R., and Mantzoros C

However, many patients maintain significant weight loss through continued healthy lifestyle habits

Kaufman worried that so many patients will drop out that the drug will be considered a failure
