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Current UK prescribing information (SmPCs) for licensed GLP-1 receptor agonists does not list a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN2) as a contraindication, though individuals with such a history should discuss this with their clinician as a precautionary measure

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Stimulating the GLP-1 receptor in the brain effectively reduces hunger, curbs cravings, and promotes a feeling of fullness after smaller meals

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