dual glp-1/gip agonist The Emerging Role of GLP-1 and GIP Receptor Agonists in Glycemic Management and Cardiovascular Risk Reduction Dual GLP-1 / GIP Receptor
Description
In DR, mitochondrial DNA leakage due to cellular stress or damage activates STING, which promotes inflammation and vascular dysfunction in retinal endothelial cells

GLP-1 drugs are a class of medications that mimic the incretin hormone GLP-1 to aid in blood sugar control and appetite regulation

Semaglutide, a selective GLP-1 receptor agonist marketed as Ozempic, Wegovy, and Rybelsus, is one of the most extensively studied anti-obesity and anti-diabetes medications in history, with over 25,000 clinical trial participants and FDA approval for three distinct indications

10.1186/s12944-017-0572-9 52

Dahmen R, Steinstraesser A, Poitiers F, Ozoux ML, Pinquier JL

Cui Y, Shi Y, Cui L, et al
