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Heres a quick rundown of the average weight loss seen in that same 72-week study: 5 mg Dose: Participants lost an average of 16% of their body weight

As results were already strongly statistically significant with these initial values, we did not add additional mice to the study under the principle of reduction in animal experiments [34]

The most common side effects are gastrointestinal, including nausea (12-24% of patients), diarrhea (12-17%), decreased appetite (10-14%), vomiting (6-12%), and constipation (11-17%)

Preclinical studies suggest that GLP1 and serotonin comodulate hypothalamic appetite regulation via alphamelanocytestimulating hormone (MSH) signalling, supporting further investigation into potential applications in anorexia nervosa and bulimia nervosa

Receptor agonists (RA) are molecules that activate a specific receptor and trigger a response

In clinical trial data for oral GLP-1 treatment, gastrointestinal side effects were common, but only a small percentage were classed as severe