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DPP-4 inhibitors prevent degradation of GLP-1 thereby increasing its systemic concentration

Emerging clinical evidence, including cardiovascular outcome studies such as the SELECT trial, suggests the therapies may reduce major cardiac events

Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver

Patients should never adjust doses without medical guidance, and treatment should be reviewed if side effects significantly impair quality of life

Aetna typically requires BMI 30 with a comorbid condition (like hypertension or sleep apnea) or BMI 35 without comorbidities, plus documented diet and exercise failure

Theres no strong evidence that Ozempic directly affects fertility, but always discuss your plans with a doctor if youre trying to conceive