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The effect of intramuscular fat on skeletal muscle mechanics: implications for the elderly and obese

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GLP-1based therapies downregulate pro-inflammatory responses in inflammatory chronic-related diseases such as diabetes, vascular diseases, neurodegenerative brain disorders, non-alcoholic steatohepatitis, nephropathy [33] and OA [17,[34], [35], [36]]

Current Evidence: GLP-1 Effects on Rheumatoid Arthritis Symptoms As of 2025, there is limited direct clinical evidence examining the effects of GLP-1 receptor agonists specifically on rheumatoid arthritis symptoms or disease progression

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In addition, exenatide plus metformin resulted in a significant reduction in CRP and TNF- compared with baseline [98]
