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Glucose decreases Na + ,K + -ATPase activity in pancreatic -cells
They are pharmacy-prepared formulations using the same active molecules but potentially different inactive ingredients, concentrations, and manufacturing processes

Davies, LixiLan-O Trial Investigators, Benefits of LixiLan, a titratable fixed-ratio combination of insulin Glargine plus Lixisenatide, versus insulin Glargine and Lixisenatide monocomponents in type 2 diabetes inadequately controlled on oral agents: The LixiLan-O randomized trial
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Exploring the mortality and cardiovascular outcomes with SGLT-2 inhibitors in patients with T2DM at dialysis commencement: a health global federated network analysis

doi:10.1016/j.clnesp.2020.04.010 11