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The standard semaglutide dosing schedule increases every four weeks, typically beginning at 0.25 mg and advancing toward therapeutic levels

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Participants will be randomized into: (1) an intervention group receiving combination therapy with the SGLT2i luseogliflozin 2.5 mg, once daily (Taisho Pharmaceutical, Tokyo, Japan) and the GLP-1 RA semaglutide 0.5 mg, once per week (Novonordisk, Copenhagen, Denmark)

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95% CI 0.580.75)

Hoge kosten van Ozempic brachten sommige verzekeringsmaatschappijen ertoe om patinten te onderzoeken en verzekering te weigeren omdat ze onvoldoende bewijs voor diabetes vonden, en veronderstelden dat het eerder diende om af te vallen