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Reduction in liver fat and improvements associated with metabolic liver disease (MASLD/MASH) in a Phase 2a study

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Common side effects include: Nausea, especially during the first few weeks at a new dose Mild diarrhea or constipation as digestion adjusts Decreased appetite, which is typically desired but can feel intense early on Occasional headaches or mild fatigue Injection site reactions like redness or light swelling Most of these effects are temporary and tend to ease as your body adjusts

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Ailin Zhang, Qinhui Liu, Yimin Xiong, Jiahui Li, Ying Xu, Haiying Song, Xiandan Jing, Haixia Xu, Na Yang, Yanping Li, Li Mo, Qin Tang, Jinhan He (2025)