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This is clearly established in the FDA drug l...

GLP-1 supplements (berberine 500mg, curcumin 1g) boost natural GLP-1 20-40% vs 0% prescription weight loss (15-20%)

Results show broad benefits with a reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses and several respiratory conditions

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In this issue of Diabetologia, Maida et al