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Drug approval package for application 215256Orig1s011 Wegovy (semaglutide)

Bi-weekly schedules reduce medication effectiveness because semaglutide's half-life is approximately 7 days, leaving you with subtherapeutic levels during the second week

A separate research letter published in JAMA identified an average percentage of days covered (PDC) of 54% in patients with obesity and without diabetes 12 months after GLP-1 RA initiation