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doi: 10.1186/s13058-015-0540-0 56 YangXKord-VarkanehHTalaeiSClarkCCTZangheliniFTanSCet al

People who have kidney problems and experience vomiting with Victoza may experience dehydration, which can worsen kidney problems

Originally developed to manage type 2 diabetes, semaglutide functions as a glucagon-like peptide-1 (GLP-1) receptor agonist, which plays a crucial role in appetite regulation and metabolic health

A dedicated phase 2a substudy in people with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) used MRI to measure liver fat and found that, after 24 weeks, retatrutide reduced relative liver-fat content by about 81% at the 8 mg dose and about 82% at 12 mg, versus essentially no change on placebo

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