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Treatment of HFpEF beyond the SGLT2-Is: Does the addition of GLP-1 RA improve cardiometabolic risk and outcomes in diabetic patients

Can J Biochem 49(8):867872 Brown J, Dryburgh J, Ross S, Dupre J (1975) Identification and actions of gastric inhibitory polypeptide

Unlike traditional GLP1 receptor agonists, tirzepatide is more selective for the GIP receptor, resulting in a more balanced activation of these receptors
However, we observed slight non-overlap between the lower limits of the confidence interval for the first and second tenths with the upper limit of the confidence interval for the last tenth

To discuss your treatment options-whether you are comparing semaglutide vs lifestyle interventions , exploring the pros and cons of medication, or considering your next steps in the GLP1 weight loss comparison -we are here to help