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Semaglutide, a GLP-1 receptor agonist, has demonstrated measurable effects on cholesterol and triglyceride levels in clinical studies

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hazard ratio 1.60, 95% CI 1.37 to 1.87) but not after confounding factors were accounted for (0.91, 0.73 to 1.12)

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Caution should be exercised in patients with a history of pancreatic disease, as well as in those with compromised renal or hepatic function

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