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Using an integrated ligand and structure-based virtual screening pipeline, explicitly combining complementary ligand-based descriptors, multi-fingerprint similarity, electrostatic similarity, pharmacophore modeling, and multi-conformation docking under a consensus-driven selection strategy, we were able to identify three chemically distinct classes of GLP-1R agonist candidates: GQB47810, a non-peptidic molecule

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BEHIND THE HYPE-- GLP-1 MEDS: We spent months digging into the benefits and costs involving GLP-1 medications

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Tradjenta (linagliptin) lowers blood sugar in adults with type 2 diabetes