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This post-hoc analysis of a phase 2b trial in adults with HIV associated lipohypertrophy reveals that semaglutide can modulate epigenetic biomarkers of aging.

Treatment with glucagon-like peptide-1 receptor agonists significantly reduced alanine aminotransferase among children with metabolic dysfunction-associated steatotic liver disease, especially those with type 2 diabetes.“MASLD is the most common chronic liver disease in children, the rates continue to rise and is the fastest growing indication for liver transplant

Semaglutide remains active in the body for approximately 7 days with a half-life of 15-19 hours, but individual clearance rates vary significantly based on metabolic biomarkers and genetic predispositions

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