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I explained that I, too, have a policy: Do not take money from me without asking

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Step 4: draw your dose Turn the vial upside down with the needle still inserted

Ironically, these findings are coming to light in an era when their relevance is diminishing, with the advent of drugs (flozins and GLP1RAs) which can be safely used below GFR 30, and which also have evidence of clinical outcome benefits

This means that the amount of the drug that causes toxic symptoms can vary between individuals depending on their age and body size