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References Tackling tolerability: The next challenge facing obesity therapies

Some patients may switch from Mounjaro to Wegovy if their clinician determines it is appropriate

GLP-1, abreviao de peptdeo semelhante ao glucagon-1, um hormnio produzido normalmente pelo intestino que ajuda a controlar o acar no sangue e o apetite aps as refeies

Macklin receives honoraria and consulting fees and serves on the national advisory boards for the manufacturers of Novo Nordisk and Eli Lilly, which makes Mounjaro, a different Type 2 diabetes drug also used for weight loss

Carbohydrates are to be eaten last

In a phase 3 trial (REDEFINE-2) of adults with T2DM and a BMI of 27 kg/m 2 and above, combining the GLP-1 receptor agonist semaglutide with the long-acting amylin analogue cagrilintide resulted in greater weight loss than placebo at 68 weeks (13.7% vs 3.4%)