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Description
31 Semaglutide has a longer aliphatic chain and increased hydrophobicity, but its hydrophilicity is greatly enhanced by PEG modification of the short chain
In one study, 2,539 overweight or obese adults (without diabetes) took tirzepatide or a placebo for 72 weeks
The analysis included trials of exenatide and liraglutide in diabetic populations and found consistent improvements in depression rating scales compared to control groups
Why is this initial physician consultation so important
If semaglutide is not absorbed properly, it may not work as well, and you might not get the full benefits of the treatment
10.1056/NEJMoa2306963 [DOI] [PubMed] [Google Scholar] 79
