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Description
Using the GLP-QR agonist Exendin-4 (Exn-4) increased firing rates in arcuate nucleus (ARC) GLP-1R and POMC neurons, and the chemogenetic activation of ARC GLP-1R neurons significantly reduced food intake [132]

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Chronic hypercortisolismwhether from endogenous Cushing's syndrome or exogenous glucocorticoid therapyproduces a characteristic metabolic phenotype
Retatrutide is an investigational injectable medicine currently undergoing clinical evaluation for the treatment of obesity and type 2 diabetes

Your protocol calls for the standard escalation starting at 0.25 mg weekly

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