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Although the study was observational, the researchers propose future clinical trials to investigate the link further.

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Itchy skin is not listed as a common side effect of semaglutide in clinical trials, but some patients report skin sensations during treatment

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Absolute and relative loss of total lean body mass, assessed via DXA scan, is often used as surrogate endpoint for measuring the impact on muscle mass, despite its obvious limitations, e.g., including the weight of organs, bones, tissue and fluids in addition to muscle
