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In a word, no

PMID: 41931082, PMCID: PMC13221856, DOI: 10.1016/j.jacadv.2026.102713.Peer-Reviewed Original ResearchAltmetricConceptsObesity medicationsDuke Clinical Research InstituteBody mass indexObesity measuresOM usePlacebo-controlled trialAnti-obesity pharmacotherapyObesity-related complicationsClinical Research InstituteEvidence-basedExpert panelMass indexDysfunctional adiposityObesity researchClinical trial designObesity pharmacotherapyObesityAction itemsOM developmentEthics of placebo-controlled trialsTrial designStreamlining researchPharmacotherapyAnti-obesityCare Naltrexone/bupropion for binge-eating disorder: A human laboratory investigation of mechanisms McKee S, Lydecker J, Pittman B, Jastreboff A , DiLeone R, Lavery M, Grilo C

Importantly, meta-analyses of randomized controlled trials have generally not shown a statistically significant increased risk of pancreatitis with GLP-1 receptor agonists as a class

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In a statement, Lilly said that it has notified the U.S

These concerns are not theoretical