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Most of these studies were conducted exclusively in male rodents
Chronic treatment of exendin-4 affects cell proliferation and neuroblast differentiation in the adult mouse hippocampal dentate gyrus
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If youre considering these medications, its worth discussing with your healthcare provider to see if theyre right for you
Intriguingly, a post hoc analysis of a phase 2 clinical trial revealed that dulaglutide treatment resulted in reductions in apoC-III and apoB levels without impacting serum LPL level, whereas treatment with tirzepatide showed a dose-dependent increase in serum LPL activity while concurrently reducing apoC-III and apoB levels ( Elevated levels of triglycerides and free fatty acids in circulation are major factors driving lipid accumulation in the liver, leading to metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis
Potential side effects, including nausea and concerns regarding long-term safety, remain under investigation
