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In this context, there is a positive correlation between fecal SCFA concentration and IBS-symptom severity, indicating that there may be an association between metabolite production and gut microbiota (Tana et al., 2010)
This has led to the development and investigation of several incretin-related therapies such as unimolecular GLP-1/glucagon receptor dual agonists, GLP-1/gastric inhibitory polypeptide (GIP) dual agonists and GLP-1/GIP/glucagon receptor triple agonists
This interaction can significantly increase bupropion levels in the blood, raising the risk of seizures, neuropsychiatric effects, and other adverse reactions
The landscape shifted with liraglutide
Cell Metab (2019) 30(5):98796.e6
