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According to a review in Diabetes Obesity Metabolism , lean muscle mass loss can range from 15% to 60% depending on the individual and intervention.47 Sarcopenia is most likely to occur in older individuals with multiple comorbidities and a larger percentage of lost body weight.47 MNT should be tailored in these cases, helping to ensure appropriate protein and caloric intake

2015Lixisenatide in patients with type 2 diabetes and acute coronary syndrome

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The estimated half-life of tizepatide is approximately 116 h, supporting its once-weekly subcutaneous administration
