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GLP-1 coverage is expanding in some ways but contracting in others

The theoretical rationale of the present study is grounded in emerging evidence that GLP-1 signaling extends beyond metabolic regulation and may influence reward processing and addiction-related neural circuits (19, 20)

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But the overall rates were still low

If we can identify and target those pathways directly, future therapies could be even more effective. Not everyone responds the same way Despite their effectiveness, GLP-1 drugs do not work equally well for everyone

A repeat colonoscopy was performed, and gross examination showed diffuse mild inflammation found from 20-40 cm proximal to the anus secondary to colitis (Figure 2)