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For weight management, NICE has approved liraglutide 3 mg (Saxenda) and semaglutide 2.4 mg (Wegovy) under specific criteria, including BMI thresholds and provision through specialist weight management services

At present, there is no NICE guidance, MHRA approval, or NHS commissioning pathway for the use of GLP-1 agonists in treating alcohol use disorder

It is normally produced in response to food intake and plays a role in insulin secretion, gastric emptying and reducing appetite
