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Escalating every 2 weeks might seem like it will get you to the effective dose faster, but it dramatically increases the risk of severe nausea, vomiting, and diarrhea that could force you to stop entirely

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Siegel KR, Ali MK, Zhou X, Ng BP, Jawanda S, Proia K, Zhang X, Gregg EW, Albright AL, Zhang P

Women with contraindications or those preferring non-hormonal options may benefit from paroxetine, fezolinetant, or off-label SSRIs/SNRIs

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To remedy this unfairness, the US could take a radical approach and say, if you, a pharmaceutical company, wish to sell your drug in the US, then if there is a supply shortage in the US, you cannot sell the drug abroad for a price below the price charged in the US
