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N Engl J Med 381(9):841851 Bethel MA, Mentz RJ, Merrill P, Buse JB, Chan JC, Goodman SG et al (2018) Renal outcomes in the EXenatide study of cardiovascular event lowering (EXSCEL)

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For individuals planning pregnancy, the optimal approach involves: Achieving target weight loss before conception attempts, allowing time to stabilise at a healthier weight Discontinuing the injection according to the product-specific timeframe before trying to conceive Transitioning to lifestyle-based weight maintenance strategies to preserve weight loss benefits Commencing folic acid supplementation (400 micrograms daily for most women

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The patient has a stable weight or is within their target weight range

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