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GLP-1/GIP Therapy Discontinuation: Why the How Matters One of the most-discussed challenges with GLP-1/GIP agonists such as tirzepatide (Mounjaro) is weight regain after stopping therapy

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GLP-1 receptor agonists trace their roots back to exendin-4, a peptide isolated from Gila monster venom in the early 1990san insight that eventually led to exenatide and reshaped the treatment of diabetes and metabolic disease