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J Clin Invest 2014;124:4223-6.ArticlePubMedPMC 100

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GLP-1 is a naturally occurring peptide that helps regulate blood sugar

Although overall findings support a cardioprotective effect of GLP-1 RAs, the ITCA 650 trial showed directionally higher hazard ratios for several outcomes

Recent evidence has revealed that endogenous signaling at the GLP-1R within the forebrain lateral septum (LS) acts to reduce cocaine-induced locomotion and cocaine conditioned place preference, both considered dopamine (DA)-associated behaviors
