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Comparison to Semaglutide: While Semaglutide acts primarily through GLP-1 receptors in the pancreas and brain, Cagrilintide targets amylin receptors in the hindbrain
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Chakraborti CK
C., Tavares, C
In particular, increased plasma insulin concentrations stimulate the gonadotropin releasing hormone (GnRH) pulsatility and potentiate the LH-dependent effect on the ovarian theca cells, leading to the enhanced synthesis of androgens and to the arrest of pre-antral follicle development [13]
