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Phase 2 CagriSema in T2D (Frias et al., 2023): CagriSema produced superior weight loss and glycemic improvement vs either monotherapy over 32 weeks

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Common and potential side effects include: Skin irritation : Redness, itching, rashes, or allergic reactions where the patch sits, especially with daily use Cardiovascular effects : Bitter orange extract can increase heart rate and blood pressure Digestive issues : Green tea extract may cause upset stomach or headaches Sleep problems : Caffeine content from green tea extract can disrupt sleep Liver concerns : Garcinia cambogia has been linked to liver problems in some cases Unknown risks : Lack of regulation means uncertain ingredient quality and quantities The bigger concern is that these products arent regulated in the same way as prescription medications