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However, some users report new or worsening gut symptoms such as nausea, vomiting and slowed digestion after starting treatment

3) review articles and animal or cell experiments

Challenges include gastrointestinal side effects, nutritional deficiencies due to calorie reduction, muscle and bone loss, low long-term adherence with subsequent weight regain, and high costs, resulting in low cost-effectiveness
39 Pancreatic beta-cells are responsible for the synthesis and secretion of insulin
