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Conclusions Severe obesity adversely influences CRC staging, operative complexity, and perioperative outcomes
This comparison is intended for research procurement and product-format review only
Fragmented care, such as receiving prescriptions from specialists without informing primary care providers, can further disrupt continuity in therapy

Policymakers, insurers, and employers must weigh the benefits of expanding access to these effective medications against the potentiallyunsustainable coststhey introduce.

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