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As its full safety profile remains under investigation, the following reflects current available data and known class effects: Gastrointestinal symptoms are the most common: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

Other at-risk populations include individuals on chronic steroids, which cause muscle wasting, patients unable to engage in strength and resistance training, or patients with muscle-wasting conditions like chronic kidney disease. McGowan also noted that even healthy individuals should expect some muscle loss

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Contrave is currently FDA-approved for the management of obesity, so call your insurance provider to see if they can assist with costs or to see if it is covered by your insurance plan

The same limitations apply to oral tirzepatide drops

Given the sheer number of cases, those involving GI injuries associated with GLP-1 drugs were consolidated into multidistrict litigation (MDL) in February 2024