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Purpose of Review This review explores the role of GLP-1 receptor agonists (GLP-1 RAs) in addressing metabolic dysfunction and neurodegeneration in Parkinsons disease (PD), focusing on body weight regulation and neuroprotection

Chronic cold stress in Glp1r-/-Gipr-/-, Glp1r-/-Glp2r-/-, and Glp2r-/- mice revealed distinct and overlapping roles for GLP-1R and GLP-2R in the expansion of the intestinal absorptive surface area expansion in response to chronic cold stress.