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Neuropeptides (2018) 71:7080

10.1001/jamaophthalmol.2024.2296 7 KanoskiS

However, a cohort study using TriNetX found that sodium-glucose co-transporter 2 inhibitors also significantly decreased the risk of new glaucoma diagnosis compared with GLP-1 RAs (HR = .932)

10.1371/journal.pone.0087488 31

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GLP-1R activation has been suggested to enhance the ability of RPE cells to counteract inflammation and oxidative stress, as RPE cells exposed to TNF-alpha and high glucose show enhanced survival characteristics following treatment with exenatide [83, 84]