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References 1 AbtahiS.HowellE.CurrieP
J Surg Oncol (2014) 109(2):16873

Vedolizumab inhibits a special integrin, alpha-4-beta-7 integrin, that is found predominantly in the gastrointestinal tract and leads to local immunosuppression in the gastrointestinal tract

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They are FDA-approved for managing type 2 diabetes and have been found effective in promoting weight loss in clinical trials

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