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Heart rate changes, though typically modest with GLP-1 therapy, deserve documentation if symptomatic

FDA: The OFA filed federal lawsuits challenging the agencys shortage resolution determinations for both tirzepatide (early 2025) and semaglutide

The peptide research landscape includes numerous compounds with varying mechanisms and efficacy profiles
Adjustments and Special Situations Dose adjustments are common when glucose targets, side effects, or kidney function change
Review the package insert for each medication

[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Mayer E.A., Tillisch K., Gupta A
