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The All of Us Research programme supplied patient data for this analysis

The bottom line GLP-1 medications can be powerful tools for weight loss, but theyre not magic bullets and where you get them matters

In turn, supplement retailers like GNC and the Vitamin Shoppe are rolling out dedicated sections that cater to GLP-1 users who are trying to maintain nutrient intake while their appetite is low

Fortunately, a tolerated treatment dose window of 150 g daily or less of cotadutide was associated with fewer adverse effects and this facilitated its progress to Phase 2 where its marked beneficial metabolic effects were observed

There is also a serotonergic component

But the interplay between the medication and mental health is complex, with many factors involved, said Dr