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Bone mineral density and effects of growth hormone treatment in prepubertal children with prader-willi syndrome: A randomized controlled trial

2022;5(10):e2235995

Although we see benefits, at what cost do the benefits come

At 50 mg to 200 mg per dose, the high injection volume requires intramuscular (IM) administration or splitting the dose across multiple subcutaneous sites

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The laboratory evidence that GLP-1 agonists increase progesterone receptor expression suggests they may actually enhance the effectiveness of progestin therapy