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We followed these patients for a median of 1.3 (interquartile range 0.6-2.8) years and 1.7 (0.7-3.7) years, respectively

For 2031, one year beyond available consensus projections, we conservatively assumed a 15% decrease in total product sales from the prior year

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The primary outcome was the incremental cost-effectiveness ratio (ICER), defined as cost per QALY gained, with the willingness-to-pay threshold set at AU$28,000 per QALY [15]

Still, this recommendation should be carefully generalized to other medicinal products, especially when treating patients with background gastroparesis or kidney dysfunction, or when considering drugs with narrow therapeutic effects