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Description
After 36 weeks, the 0.5 mg retatrutide group showed a 3.19% body weight reduction, the 4 mg group showed a 10.37% decrease, the 8 and 12 mg groups demonstrated decreases of 16.81% and 16.94% respectively, which were significantly greater than those observed with placebo (3.00%) and 1.5 mg dulaglutide (2.02%) [114]

According to the U.S

Participants who began at 2 mg reported milder nausea, less vomiting, and fewer instances of diarrhea during the escalation phase
But these drugs have a much longer history

According to a January 2024 report from the Health and Human Services' Office of the Assistant Secretary for Planning and Evaluation, the prices across all drugs in the United States were at least 2.78 times higher than in comparison countries and at least 3.22 times as high for brand drugs

Stat Med 33(7):124258
