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fda approved glp-1 agonists New Pill Foundayo (Orforglipron) Gets Approval for Obesity The New Weight Management Meds
Description
In all patients, there was a 44% reduction in risk of colorectal cancer when using GLP-1RAs as compared to insulin, and a 25% reduction in risk as compared to metformin use

2024 Jan-Feb;64(1):133-138

Consistent with these findings, peripherally administered CCK induces cFos immunoreactivity in GLP-1-producing neurons of the hindbrain vagal complex of the NTS [354], and surgical vagal deafferentation reduces CCK-induced NTS neuronal cFos activation by approximately 50% [355]

It might be time for a different approach

10.2174/1573399810666140707092506 [DOI] [PubMed] [Google Scholar] 20

John Pisano never got to see his obsession with venom become the basis for the blockbuster drug of the century
