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Novo is continuing to bolster its obesity portfolio, recently inking a $2.1 billion collaboration with biotech Vivtex to develop next-generation oral obesity pills as part of a push from injectables to more convenient formulations

The range reflects a difference in assumptions: Do GLP-1s prevent diabetes for four years (similar to clinical trial results) or will these benefits extend over a lifetime

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The dysesthesia signal is concerning and needs more investigation

RRID:AB_628490)

Estimated mean changes in HbA 1c and BW were 0.88%-points (95% confidence interval [CI] 1.01 to 0.75