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This occurs through the phosphorylation of myosin light chain (MLC) by ROCK, resulting in cytoskeletal reorganization and changes in endothelial cell adhesion

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Marx N., Burgmaier M., Heinz P., Ostertag M., Hausauer A., Bach H., Durst R., Hombach V., Walcher D

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In other words, its always easier to prevent than it is to treat

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