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Journal of Physiology (London), 588(24), 48714889

This was a phenomenal discovery, since primate-specific Trp33 ECD served as a critical point in the binding of small molecules, whereas it is not a critical component for the activation of the GLP-1 receptor by native GLP-1

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This review examines metabolic adaptations during GLP-1RA therapy and their implications for nutritional and redox homeostasis

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