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Your legs might look like the vein disease got worse when really the veins were already there just masked by surrounding fat tissue

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Qualifying criteria include BMI greater than 27 with prediabetes or established cardiovascular disease, or BMI over 30 with uncontrolled hypertension, advanced kidney disease, or heart failure

Despite these encouraging trends, the market has hurdles, including due to the high cost of GLP-1 agonists, which may limit access for specific patient populations

Holst, a gastrointestinal surgeon, had been hooked on finding the missing incretin for more than a decade ever since hed seen bariatric surgery patients at his hospital experiencing surges in insulin and crashing blood sugar