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Background and Aim The association between biliary disorders with weight reduction enhanced by GLP-1RAs was observed frequently, nevertheless, the relative risk of the clinically relevant cholelithiasis was not specified clearly among different GLP-1RAs

The primary analysis was an intention-to-treat analysis

Several patterns appear consistently: Loss of lean muscle mass Inadequate protein intake Nutrient deficiencies, particularly vitamin D and magnesium This matters because muscle mass plays a direct role in supporting skeletal health